EDEM1 Polyclonal Antibody, 100ul Filtration PubMed: 20233726

PubMed: 20233726

It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML

Multiple transcript variants encoding different isoforms have been found for FLT1

In neck and head squamous cell carcinomas

EDEM1 Polyclonal Antibody, 100ul Filtration PubMed: 20233726Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N glycan dependent manner. It lacks mannosidase activity.,Belongs to the glycosyl hydrolase 47 family.,subunit: Interacts with DERL2 and DERL3.,