PUMA Polyclonal Antibody, 100ul Dry Bath This gene belongs to the

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs

a tumor suppressor

|Contains 1 BTB (POZ) domain

Contains 1 importin N-terminal domain

PUMA Polyclonal Antibody, 100ul Dry Bath This gene belongs to theBBC3 encodes a member of the BCL 2 family of proteins. This family member belongs to the BH3 only pro apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti apoptotic Bcl 2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro apoptotic role, BBC3 is a potential drug target for cancer