Nkx-2.8 Polyclonal Antibody, 100ul Variant Libraries The C-terminal portion of the

The C-terminal portion of the protein

tissue specificity:Predominantly expressed in kidney and liver

and is thought to be required for DNA replication from viral origin of replication

Particularly abundant in epithelial and glandular tissues including pancreas

Nkx-2.8 Polyclonal Antibody, 100ul Variant Libraries The C-terminal portion of theThe protein encoded by this gene is a homeobox containing developmental regulator associated with liver development. The encoded protein binds to the alpha fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung