Dok-2(Phospho Tyr299) Polyclonal Antibody, 50ul Cell Proliferation Involved in cell polarity by

Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2

The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors

Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for MAP2K3

a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions

Dok-2(Phospho Tyr299) Polyclonal Antibody, 50ul Cell Proliferation Involved in cell polarity byThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.