Human 26S Proteasome Non-atpase Regulatory Subunit 4, PSMD4 ELISA Kit , 96T Live Cell Imaging Mutations in this gene are

Mutations in this gene are associated with microvillous inclusion disease

Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway

this protein can also serve as a transcriptional repressor

Variation in this gene has been associated with cerebellar ataxia

Human 26S Proteasome Non-atpase Regulatory Subunit 4, PSMD4 ELISA Kit , 96T Live Cell Imaging Mutations in this gene areComponent of the 26S proteasome, a multiprotein complex involved in the ATP dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression,