FTO Polyclonal Antibody, 20ul ADME The protein encoded by KRT2
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FTO Polyclonal Antibody, 20ul ADME The protein encoded by KRT2FTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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