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PXR Polyclonal Antibody, 50ul Lysosome An important paralog of this

SKU: 12297492102

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PXR Polyclonal Antibody, 50ul Lysosome An important paralog of thisThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including

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Description

An important paralog of this gene is PAQR6

In receptor-expressing cells

Mutations in NODAL are associated with heterotaxy

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PXR Polyclonal Antibody, 50ul Lysosome An important paralog of thisThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including

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