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Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Several pseudogenes of this gene

SKU: 12890800016

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Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Several pseudogenes of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Several pseudogenes of this gene have been identified

COMT is important in the metabolism of catechol drugs used in the treatment of hypertension

The organ- and cell-specific expression of ACE2 suggests that it may play a role in the regulation of cardiovascular and renal function

Alternate splicing results in both coding and non-coding variants

Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Several pseudogenes of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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