Shc(Phospho Tyr427) Polyclonal Antibody, 100ul Monoclonal Antibody Preparation and also has been shown

and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity

In mitosis RCC1 is phosphorylated at Ser11

which may be partly responsible for the protection against cell death

Contains 2 fibronectin type-III domains

Shc(Phospho Tyr427) Polyclonal Antibody, 100ul Monoclonal Antibody Preparation and also has been shownThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.