Raf-B Monoclonal Antibody, 100ul[BT-MCA1089] Monoclonal Antibody Preparation Two alternatively spliced transcript variants

Two alternatively spliced transcript variants encoding distinct isoforms have been found

MIF encodes a lymphokine involved in cell-mediated immunity

The encoded protein interacts with many other proteins| including the platelet integrin alpha-IIb-beta-3| DNA-dependent protein kinase| presenilin-2| focal adhesion kinase| p21 activated kinase| and protein kinase D

This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription

Raf-B Monoclonal Antibody, 100ul[BT-MCA1089] Monoclonal Antibody Preparation Two alternatively spliced transcript variantsThis gene encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been