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TAF II p100 Polyclonal Antibody, 50ul Protein Research |PTM:During G0 and early G1

SKU: 13330791436

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TAF II p100 Polyclonal Antibody, 50ul Protein Research |PTM:During G0 and early G1Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Transcription initiation factor TFIID subunit 5 that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA

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Description

|PTM:During G0 and early G1 phase of the cell cycle| phosphorylated on Ser-639 and on 5 sites within the domain B

and is associated with several disease states including cancer and Alzheimer's disease

Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling

The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer

TAF II p100 Polyclonal Antibody, 50ul Protein Research |PTM:During G0 and early G1Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Transcription initiation factor TFIID subunit 5 that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA

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