Presenilin 1 Polyclonal Antibody, 50ul Biomatrix RPL28 encodes a ribosomal protein

RPL28 encodes a ribosomal protein that is a component of the 60S subunit

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CDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors

This gene encodes both membrane-bound and secreted protein isoforms

Presenilin 1 Polyclonal Antibody, 50ul Biomatrix RPL28 encodes a ribosomal proteinAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.