Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes the encoded protein is a

the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation

and may modify the risk of Alzheimer's disease

The protein is implicated in several signal transduction pathways including the Stat pathway

The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1

Stat4(Phospho Tyr693) Polyclonal Antibody, 100ul[BT-AP14540] Culture Tubes the encoded protein is aThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.