DOC11 Polyclonal Antibody, 20ul Protein Expression ARHGAP18 belongs to a family

ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al

such as HIV-1: acts by inhibiting an early step of viral infection

this kinase is known to be involved in many cellular processes including stress and inflammatory responses

and intestines

DOC11 Polyclonal Antibody, 20ul Protein Expression ARHGAP18 belongs to a familyThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,