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RFOX1 Polyclonal Antibody, 100ul Peptide Synthesis The encoded protein is found

SKU: 14826618078

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SEK123.75 SEK148.75

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RFOX1 Polyclonal Antibody, 100ul Peptide Synthesis The encoded protein is foundThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

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Description

The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane

It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses

heparin sulfate

A related pseudogene exists on chromosome X

RFOX1 Polyclonal Antibody, 100ul Peptide Synthesis The encoded protein is foundThe Fox 1 family of RNA binding proteins is evolutionarily conserved, and regulates tissue specific alternative splicing in metazoa. Fox 1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C terminus of ataxin 2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin 2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox 1 and ataxin

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