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S10AE Polyclonal Antibody, 20ul Biochemical Reagents This gene is a candidate

SKU: 15346571237

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SEK97.20 SEK146.20

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S10AE Polyclonal Antibody, 20ul Biochemical Reagents This gene is a candidateThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).

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Description

This gene is a candidate for the ovarian tumor suppressor gene

Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5)

Dysregulation of this gene has been associated with the growth and progression of certain cancers

It mediates adhesive interactions important for antigen-specific immune response

S10AE Polyclonal Antibody, 20ul Biochemical Reagents This gene is a candidateThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).

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