TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging but lacks the active site
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TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging but lacks the active siteCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only
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