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PKN Polyclonal Antibody, 100ul Serum Deficiency in this protein (B-cell

SKU: 15679451095

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PKN Polyclonal Antibody, 100ul Serum Deficiency in this protein (B-cellThe protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The

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Description

Deficiency in this protein (B-cell linker)has also been shown in some cases of pre-B acute lymphoblastic leukemia

Through a phosphatidylinositol-calcium second messenger system

Defects in this gene are a cause of Walker-Warburg syndrome (WWS)

Mutations in this gene are a cause of spastic ataxia 2

PKN Polyclonal Antibody, 100ul Serum Deficiency in this protein (B-cellThe protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3 phosphoinositide dependent protein kinase 1 (PDPK1 PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The

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