DCTN4 Polyclonal Antibody, 50ul Lentiviral Packaging Spastic paraplegias are a diverse

Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive| lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts

the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes

The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling

F9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen

DCTN4 Polyclonal Antibody, 50ul Lentiviral Packaging Spastic paraplegias are a diverseCould have a dual role in dynein targeting and in ACTR1A Arp1 subunit of dynactin pointed end capping. Could be involved in ACTR1A pointed end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,Belongs to the dynactin subunit 4 family.,subcellular location: Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization