ATD3A Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection Mutations in paired box gene

Mutations in paired box gene 3 are associated with Waardenburg syndrome

the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex

while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1

This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases

ATD3A Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection Mutations in paired box geneATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA) protein complexes called nucleoids (He et al., 2007