SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene cause

Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA)

and modulation of cell growth

The dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

SPZ1 Polyclonal Antibody, 100ul Mechanical Pipette Mutations in this gene causeSPZ1 (spermatogenic leucine zipper 1) encodes a bHLH zip transcription factor which functions in the mitogen activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, SPZ1 may serve as a target for Ras induced tumor treatments.