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Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03355] Gene Synthesis indicating the implication of this

SKU: 16998973231

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Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03355] Gene Synthesis indicating the implication of thisFZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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Description

indicating the implication of this gene in postmenopausal osteoporosis

Activity of this protein is important in the epithelial to mesenchymal transition

whereas the others act as auxiliary subunits regulating this activity

Seems to negatively regulate the level of HIF1A expression

Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03355] Gene Synthesis indicating the implication of thisFZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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