HMX2 Polyclonal Antibody, 20ul Polyclonal Antibodies AKR1C3 shares high sequence identity

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

Contains 1 Ig-like V-type (immunoglobulin-like) domain

This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes

Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions

HMX2 Polyclonal Antibody, 20ul Polyclonal Antibodies AKR1C3 shares high sequence identityThe protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.