SREC Polyclonal Antibody, 100ul Pathway and Network Analysis Dimerization with alphaE permits binding

Dimerization with alphaE permits binding to the ligand epithelial cadherin

Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains

MIM 163729)| and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures| thereby attenuating ENOS-dependent NO production

These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them

SREC Polyclonal Antibody, 100ul Pathway and Network Analysis Dimerization with alphaE permits bindingThe protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444 EZF 2 and SP1. Alternative splicing results in multiple transcript variants.