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DDX3 Polyclonal Antibody, 50ul[BT-AP02542] Human Genome Knockout Libraries Mutations in this gene cause

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DDX3 Polyclonal Antibody, 50ul[BT-AP02542] Human Genome Knockout Libraries Mutations in this gene causeDEAD box helicase 3, X linked encoded by DDX3X is a member of the large DEAD box protein family, that is defined by the presence of the conserved Asp Glu Ala Asp (DEAD) motif, and has ATP dependent RNA helicase activity. This protein has been reported to display a high level of RNA independent ATPase activity, and unlike most DEAD box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved

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Description

Mutations in this gene cause selective T-cell defect| a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells

Binds TCF4 and RB1

The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis

They share target genes

DDX3 Polyclonal Antibody, 50ul[BT-AP02542] Human Genome Knockout Libraries Mutations in this gene causeDEAD box helicase 3, X linked encoded by DDX3X is a member of the large DEAD box protein family, that is defined by the presence of the conserved Asp Glu Ala Asp (DEAD) motif, and has ATP dependent RNA helicase activity. This protein has been reported to display a high level of RNA independent ATPase activity, and unlike most DEAD box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved

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