V1RL2 Polyclonal Antibody, 100ul Plasma GRAP encodes a member of

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

Seems to play an essential role in cold-induced suppression of cell proliferation

The other two isoforms

V1RL2 Polyclonal Antibody, 100ul Plasma GRAP encodes a member ofFUNCTION: putative pheromone receptor. SUBCELLULAR LOCATION: cell membrane; Multi pass membrane protein. MISCELLANEOUS: the chimpanzee, gorilla and orangutan orthologous proteins do not exist, their genes are pseudogenes.