B23 Polyclonal Antibody, 50ul Drug Development and Evaluation Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for POU2F2

Cytokine that induces the release of T cell-attracting chemokines from monocytes and| in particular| enhances the maturation of CD11c(+) dendritic cells

Mutations in CIDEC may contribute to insulin resistant diabetes

Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms

B23 Polyclonal Antibody, 50ul Drug Development and Evaluation Several transcript variants encoding differentNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.