ARP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Mutations at this locus have

Mutations at this locus have been associated with Rett syndrome

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family

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ARP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Mutations at this locus haveMesencephalic astrocyte derived neurotrophic factor encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N terminal arginine rich region, including a specific