NOSTN Rabbit Polyclonal Antibody, 50ul Glassware These peptides act as autocrine

These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system

and it has been determined that the diseased allele contains 40-83 CAG repeats

This gene is localized to human chromosome 16p13

The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes

NOSTN Rabbit Polyclonal Antibody, 50ul Glassware These peptides act as autocrineNitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission inflammatory response and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production endothelial NO synthase (ENOS; MIM 163729) and triggers the translocation of ENOS from the plasma membrane to vesicle like subcellular structures thereby attenuating ENOS dependent NO production.