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INT8 Rabbit Polyclonal Antibody, 50ul Hepatocytes Spectrins are composed of alpha

SKU: 18894056169

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INT8 Rabbit Polyclonal Antibody, 50ul Hepatocytes Spectrins are composed of alphaThis gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants.

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Description

Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement

Uniform thickness of plate bottom and well size

Mutations in this gene cause myopathy and distal arthrogryposis type 2B

Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN

INT8 Rabbit Polyclonal Antibody, 50ul Hepatocytes Spectrins are composed of alphaThis gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants.

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