SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction It is localized in the

It is localized in the Down syndrome critical region of chromosome 21

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

offering minimal sample retention and enhanced reproducibility

It functions as a transcriptional repressor

SOCS-3 Polyclonal Antibody, 20ul Nucleic Acid Extraction It is localized in theThis gene encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse