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Alternatively spliced transcript variants that encode different proteins have been identified

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This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13

G Alpha i-3 Polyclonal Antibody, 20ul Digital Burette Order now and experience theGuanine nucleotide binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. GNAI3 encodes an alpha subunit and belongs to the G alpha family. Mutation in this gene, resulting in a gly40 to arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein coupled endothelin receptor