SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes The paired box 4 gene

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

Many alternatively spliced transcript variants exist for this gene

constituting the KDEL receptor gene family

They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al

SGCG Rabbit Polyclonal Antibody, 20ul Sampling Tubes The paired box 4 geneThis gene encodes gamma sarcoglycan one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin syntrophin alpha and beta dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset