PFK-2 car(Phospho Ser483) Polyclonal Antibody, 100ul Plasmid Preparation This gene encodes a member

This gene encodes a member of the GXGD family of aspartic proteases| which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions| as well as a member of the signal peptide peptidase-like protease (SPPL) family

Several transcript variants encoding different isoforms have been described for this gene

Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD)

is expressed in CNS and testis

PFK-2 car(Phospho Ser483) Polyclonal Antibody, 100ul Plasmid Preparation This gene encodes a memberThe protein encoded by this gene is involved in both the synthesis and degradation of fructose 2,6 bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6 phosphofructo 2 kinase activity that catalyzes the synthesis of fructose 2,6 bisphosphate, and a fructose 2,6 biphosphatase activity that catalyzes the degradation of fructose 2,6 bisphosphate. This protein regulates fructose 2,6 bisphosphate levels in