FAK(Phospho Tyr925) Polyclonal Antibody, 100ul Subcellular Fractions Beare-Stevenson cutis gyrata syndrome

Beare-Stevenson cutis gyrata syndrome

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

which activates NF-kappa-B by making it available to translocate to the nucleus

A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes

FAK(Phospho Tyr925) Polyclonal Antibody, 100ul Subcellular Fractions Beare-Stevenson cutis gyrata syndromeThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal