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Raf-1 Polyclonal Antibody, 20ul[BT-AP13533] Modified Oligos Expression of this gene is

SKU: 20101059851

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Raf-1 Polyclonal Antibody, 20ul[BT-AP13533] Modified Oligos Expression of this gene isThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Expression of this gene is highly restricted

characterized by hypertriglyceridemia

Their diverse functions include regulating neurotransmitter release| heart rate| insulin secretion| neuronal excitability| epithelial electrolyte transport| smooth muscle contraction| and cell volume

Overexpression of cortactin increases cell migration

Raf-1 Polyclonal Antibody, 20ul[BT-AP13533] Modified Oligos Expression of this gene isThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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