I10R2 Polyclonal Antibody, 100ul Monoclonal Antibodies This protein binds to DNA

This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE)

Mutations in this gene are associated with sarcosinemia

craniofacial development

This gene may be associated with many disease states

I10R2 Polyclonal Antibody, 100ul Monoclonal Antibodies This protein binds to DNAThe protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10 induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.