MKRN1 Rabbit Polyclonal Antibody, 100ul Pipette Filler Mutations in this gene are

Mutations in this gene are the cause of Wagner syndrome type 1

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress

Parkinson's disease

each of which contains a highly specific cleavage signal

MKRN1 Rabbit Polyclonal Antibody, 100ul Pipette Filler Mutations in this gene areThis gene encodes a protein that belongs to a novel class of zinc finger proteins. The encoded protein functions as a transcriptional co regulator and as an E3 ubiquitin ligase that promotes the ubiquitination and proteasomal degradation of target proteins. The protein encoded by this gene is thought to regulate RNA polymerase II catalyzed transcription. Substrates for this protein's E3 ubiquitin ligase activity include the capsid protein of the West