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IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification Two alternative transcripts encoding the

SKU: 2049968314

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IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification Two alternative transcripts encoding theIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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Description

Two alternative transcripts encoding the same protein have been described

Most lipocalins are clustered on the long arm of chromosome 9

it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520)

and may play a role in the development of artherosclerosis and rheumatoid arthritis

IRS-1 Polyclonal Antibody, 100ul[BT-AP04647] Purification Two alternative transcripts encoding theIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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