Caspase-8 Monoclonal Antibody(2G12), 20ul Proteases and mutations in SLC25A12 may
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Caspase-8 Monoclonal Antibody(2G12), 20ul Proteases and mutations in SLC25A12 mayThis gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large
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