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VN2R1P Polyclonal Antibody, 50ul Reservoirs Solute carrier family 22 member

SKU: 2141753353

4.4
DKK162.00 DKK204.00

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VN2R1P Polyclonal Antibody, 50ul Reservoirs Solute carrier family 22 memberThe CARL 1 monoclonal antibody reacts with human TWEAK, a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion. TWEAK transcript is expressed broadly in many adult and fetal tissues, however, the staining of human peripheral blood mononuclear cells with monoclonal antibodies shows a more restricted pattern. While freshly isolated PBMCs do not express detectable levels of TWEAK on their surface, IFN gamma

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Description

Solute carrier family 22 member 3 contains twelve putative transmembrane domains and is a plasma integral membrane protein

Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly

and some variations in CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS

As shown for the yeast homolog| which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases| this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors

VN2R1P Polyclonal Antibody, 50ul Reservoirs Solute carrier family 22 memberThe CARL 1 monoclonal antibody reacts with human TWEAK, a type II transmembrane TNF superfamily member with high identity to TNF in its extracellular portion. TWEAK transcript is expressed broadly in many adult and fetal tissues, however, the staining of human peripheral blood mononuclear cells with monoclonal antibodies shows a more restricted pattern. While freshly isolated PBMCs do not express detectable levels of TWEAK on their surface, IFN gamma

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