Rat Mothers Against Decapentaplegic Homolog 2, SMAD2 ELISA Kit, 96T Mini dry bath 6-dihydroxyindole-2-carboxylate
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Rat Mothers Against Decapentaplegic Homolog 2, SMAD2 ELISA Kit, 96T Mini dry bath 6-dihydroxyindole-2-carboxylateReceptor regulated SMAD (R SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF beta and, on formation of the SMAD2 SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by
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