PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Both Ikaros and Aiolos can

Both Ikaros and Aiolos can participate in chromatin remodeling

The encoded preproprotein is proteolytically processed to generate the mature enzyme

The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization

with or without motor neuropathy

PHLD Polyclonal Antibody, 50ul Reagent Reservoirs Both Ikaros and Aiolos canMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma