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PGS1 Polyclonal Antibody, 20ul Shaker&Mixing In a non-canonical activation pathway|

SKU: 22193264160

4.6
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PGS1 Polyclonal Antibody, 20ul Shaker&Mixing In a non-canonical activation pathway|This gene encodes a member of the small leucine rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve

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Description

In a non-canonical activation pathway| the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB| inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes

in de novo pyrimidine biosynthesis

This gene was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene

The product of NCBP2 is a component of the nuclear cap-binding protein complex (CBC)

PGS1 Polyclonal Antibody, 20ul Shaker&Mixing In a non-canonical activation pathway|This gene encodes a member of the small leucine rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve

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