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CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture Alternatively spliced transcript variants have

SKU: 22200865782

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CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture Alternatively spliced transcript variants haveCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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Description

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

the ability of CCL4 to bind CCR5 inhibits the cellular entry of M-tropic HIV-1 which utilizes CCR5 as a co-receptor

Receptor on natural killer cells

They are differentially expressed in normal tissues

CD55 Polyclonal Antibody, 100ul[BT-AP02079] 3D Culture Alternatively spliced transcript variants haveCOL25A1 (collagen type XXV alpha 1 chain) encodes a brain specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over expression of this collagen in mice, however, found changes in pathology

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