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Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette Mutations at GCLC have been

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Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette Mutations at GCLC have beenALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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Description

Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction

The inserts have three side openings design that facilitates easy access for tests and allows for gas exchange in the culture environment

the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation

Also| chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

Phospho-5-LO (S523) Polyclonal Antibody, 50ul Digital Burette Mutations at GCLC have beenALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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