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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivator

SKU: 22524951583

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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivatorThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Acts as a transcriptional coactivator of serum response factor (SRF)

This gene encodes a replication-dependent histone that is a member of the histone H2B family| and generates two transcripts through the use of the conserved stem-loop termination motif| and the polyA addition motif

Three members of this protein family (Ikaros

Several transcripts encoding different isoforms have been found for this gene

p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Acts as a transcriptional coactivatorThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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