PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification Get ready to flip and
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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification Get ready to flip andCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,
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