RILP Polyclonal Antibody, 20ul General Lab Use A Ser310Ala polymorphism has been

A Ser310Ala polymorphism has been associated with schizophrenia| and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides

Its initiating methionine residue is post-translationally removed

RILP Polyclonal Antibody, 20ul General Lab Use A Ser310Ala polymorphism has beenThis gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.