CD34 Monoclonal Antibody, 100ul Funnels Mutations in this gene are

Mutations in this gene are associated with osteogenesis imperfecta types I-IV| Ehlers-Danlos syndrome type VIIA| Ehlers-Danlos syndrome Classical type| Caffey Disease and idiopathic osteoporosis

It is not expressed in normal tissues

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta

This gene plays a crucial role in neural crest development

CD34 Monoclonal Antibody, 100ul Funnels Mutations in this gene areThe protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene.